Linked Life Data

4085553

Source:http://linkedlifedata.com/resource/pubmed/id/4085553

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1986-3-5
pubmed:abstractText
Pretreatment with graded doses of adenosine (0.1-1.0 mg), injected close-arterially (i.a.) to the vascularly isolated and self-hemoperfused dog pancreas, increased secretin (0.025 units i.a.)-stimulated secretory volume dose dependently and this effect of adenosine was reversed by further pretreatment with theophylline (0.3 mg i.a.). Adenosine itself did not affect the rate of resting secretion and the concentrations of protein and bicarbonate of the resting pancreatic juice. Adenosine decreased the concentration of protein and increased that of bicarbonate in the pancreatic juice stimulated by secretin. Adenosine, however, did not affect dopamine (3 micrograms i.a.)-stimulated pancreatic secretion. Adenosine (0.1-1.0 mg i.a.)-induced vasodilation was also reversed by the pretreatment with theophylline (0.3 mg i.a.). These results suggest the existence of adenosine 'R' receptors in the exocrine cells and the vasculature of the dog pancreas.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0014-2999
pubmed:author
pubmed:issnType
Print
pubmed:day
3
pubmed:volume
118
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
203-9
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Adenosine potentiates secretin-stimulated pancreatic exocrine secretion in the dog.
pubmed:publicationType
Journal Article