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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5-6
|
| pubmed:dateCreated |
1986-1-28
|
| pubmed:abstractText |
Patients suffering from chronic external otitis had developed contact allergies to one or more compounds of topical preparations in 40% of 142 tested patients. Neomycin and framycetin caused most of the allergic reactions (16.2%) followed by chinoform (7.0%), chloramphenicol and polymyxin (4.2%). Preservatives of the topical otic preparations such as benzethonium chloride (8.5%), benzalkonium chloride (6.3%) and thimerosal (merthiolate) (5.6%) were also common causes of allergic reactions. An epicutaneous test (patch test) using compounds in topical preparations should be done in cases of prolonged, treatment resistant external otitis.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0001-6489
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
100
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
414-8
|
| pubmed:dateRevised |
2010-11-18
|
| pubmed:meshHeading |
pubmed-meshheading:4082979-Anti-Infective Agents, Local,
pubmed-meshheading:4082979-Dermatitis, Contact,
pubmed-meshheading:4082979-Framycetin,
pubmed-meshheading:4082979-Humans,
pubmed-meshheading:4082979-Neomycin,
pubmed-meshheading:4082979-Otitis Externa,
pubmed-meshheading:4082979-Patch Tests,
pubmed-meshheading:4082979-Pharmaceutical Vehicles
|
| pubmed:articleTitle |
Contact allergy to various components of topical preparations for treatment of external otitis.
|
| pubmed:publicationType |
Journal Article
|