Linked Life Data

4080711

Source:http://linkedlifedata.com/resource/pubmed/id/4080711

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1986-2-7
pubmed:abstractText
We have detected an endogenous digoxin-immunoreactive substance in the blood of third trimester pregnant women, of newborn infants and in amniotic fluids. In this report we present data showing an increase in blood levels of this endogenous substance in pregnant women with time of gestation (45 +/- 12, 125 +/- 32, and 195 +/- 27 pg/ml digoxin-equivalent for the 1st, 2nd, and 3rd trimesters, respectively, mean +/- SE). Preliminary evidence suggests the blood level of this substance is elevated in third-trimester hypertensive pregnant women (315 +/- 29 pg/ml). The immunoactive substance isolated from pregnant subjects is water soluble and reversibly bound to serum proteins. Heating the serum increases the measured immunoactivity. Exploration of the physiologic relevance of this endogenous substance or family of substances is in progress.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0361-7742
pubmed:author
pubmed:issnType
Print
pubmed:volume
192
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
229-32
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Endogenous digoxin immunoactivity is elevated in hypertensive pregnancy.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't