Linked Life Data

4080516

Source:http://linkedlifedata.com/resource/pubmed/id/4080516

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1986-2-7
pubmed:abstractText
Short duration washin and washout experiments were carried out with the gases ether (diethyl ether), ethyl acetate and acetone in order to study the excretion behaviour in the lung of gases highly soluble in blood and tissues. Carbon dioxide (CO2) was analyzed as a reference gas during the washout. The excretion values for acetone were generally the lowest, those for ether the highest, and intermediate ones were obtained for ethyl acetate. These results are in accord with the experimental data of others. Analysis of the washout curves shows that for acetone the volume of gas expired before the beginning of phase II is considerably smaller than found for CO2 and ether. During washout, the slope of the alveolar plateau for acetone is negative for the first few breaths and becomes positive thereafter; however, it remains lower than the slopes for CO2 and ether, which are always positive. These two phenomena occurring during washout clearly demonstrate that the acetone in the expired air must originate from the epithelial tissue lining the conducting airways. We conclude, therefore, that, in terms of gas transport, the conducting airways behave differently for poorly and highly soluble gases and this provides a physiological basis for the deviating excretion behaviour of highly soluble gases.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0031-6768
pubmed:author
pubmed:issnType
Print
pubmed:volume
405
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
389-94
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Uptake of highly soluble gases in the epithelium of the conducting airways.
pubmed:publicationType
Journal Article