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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
3
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pubmed:dateCreated |
1986-2-19
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pubmed:abstractText |
Initiation factor 2 from adult rat brain was isolated from salt-washed microsomes using a three-step purification process consisting of heparin-Sepharose, phosphocellulose and diethylaminoethyl-cellulose (DEAE cellulose) column chromatographies. The initiation factor 2(eIF-2) was phosphorylated in subunits alpha and beta by the endogenous protein kinase activity present in the pruified preparation. This protein kinase activity proved to be mostly a casein kinase, although the possible presence of a very specific alpha kinase activity cannot be dismissed.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0304-3940
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
11
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
333-7
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:4080266-Animals,
pubmed-meshheading:4080266-Brain,
pubmed-meshheading:4080266-Brain Chemistry,
pubmed-meshheading:4080266-Caseins,
pubmed-meshheading:4080266-Catalysis,
pubmed-meshheading:4080266-Eukaryotic Initiation Factor-2,
pubmed-meshheading:4080266-Histones,
pubmed-meshheading:4080266-Peptide Initiation Factors,
pubmed-meshheading:4080266-Phosphorylation,
pubmed-meshheading:4080266-Protein Kinases,
pubmed-meshheading:4080266-Proteins,
pubmed-meshheading:4080266-Rats,
pubmed-meshheading:4080266-Substrate Specificity
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pubmed:year |
1985
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pubmed:articleTitle |
Initiation factor 2 isolated from rat brain contains kinase activities responsible for its phosphorylation.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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