Linked Life Data

4074400

Source:http://linkedlifedata.com/resource/pubmed/id/4074400

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1986-1-15
pubmed:abstractText
The data available in literature on the structure-activity relationships in the series of muscarinic antagonists have been analyzed. Three groups of the ammonium compounds are distinguished, each containing a specific chemical structure element. For the antagonist association with the receptor, the binding constant logarithms within each group depend linearly on the partition coefficient (pi) logarithms characterizing their distribution in the water-octanol system. The linear regression coefficients for pi are practically identical. A separate group consists of antagonists that have no ammonium grouping. Four possible modes of antagonist-receptor binding are surmized.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0132-3423
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1402-16
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
[Structure-activity relationship in the series of muscarinic acetylcholine receptor antagonists: four types of antagonist-receptor binding].
pubmed:publicationType
Journal Article, In Vitro, English Abstract