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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
3
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pubmed:dateCreated |
1986-1-8
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pubmed:abstractText |
An inward-directed proton gradient energizes the transport of intact glycylsarcosine against a concentration gradient in rabbit renal brush-border membrane vesicles. Dissipation of the proton gradient abolishes the uphill transport. Generation of an inside-negative membrane potential nearly doubles the intravesicular concentration of the dipeptide at the peak of the overshoot without altering the equilibrium value. These data provide direct evidence for peptide-proton cotransport in the renal brush-border membrane.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Nov
|
|
pubmed:issn |
0006-291X
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
15
|
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pubmed:volume |
132
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
946-53
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:4074356-Animals,
pubmed-meshheading:4074356-Biological Transport, Active,
pubmed-meshheading:4074356-Dipeptides,
pubmed-meshheading:4074356-Glycylglycine,
pubmed-meshheading:4074356-Hydrogen-Ion Concentration,
pubmed-meshheading:4074356-Hydrolysis,
pubmed-meshheading:4074356-Ionophores,
pubmed-meshheading:4074356-Kidney,
pubmed-meshheading:4074356-Membrane Potentials,
pubmed-meshheading:4074356-Microvilli,
pubmed-meshheading:4074356-Rabbits,
pubmed-meshheading:4074356-Sodium
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pubmed:year |
1985
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pubmed:articleTitle |
Proton gradient-coupled uphill transport of glycylsarcosine in rabbit renal brush-border membrane vesicles.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.
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