Linked Life Data

4072631

Source:http://linkedlifedata.com/resource/pubmed/id/4072631

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1985-12-31
pubmed:abstractText
The aim of the study was to clarify if these diabetics, with the greatest risk for development of proliferative retinopathy, could be identified by early measurement of urinary albumin excretion (UAE), using sensitive methods. In addition, the possible role of blood pressure was assessed. All male diabetics originally examined in 1969-1976 were re-examined by measuring UAE and blood pressure together with an ordinary ophthalmoscopic examination. Patients fulfilling the following criteria were incorporated in the study: age at diagnosis of diabetes less than 20 years; initial duration of diabetes 7-20 years; follow-up period greater than 7 years, and no clinical proteinuria. 44 patients were identified, all but one accepted re-examination. 29 patients initially had UAE less than 15 micrograms/min, one of these developed proliferative retinopathy. 14 patients initially had UAE greater than or equal to 15 micrograms/min, 9 of these developed proliferative retinopathy. Blood pressure was elevated both initially and at follow-up in diabetics showing progression to proliferative retinopathy. It is concluded that even a slightly elevated UAE 'micro-albuminuria', is a strong predictor with respect to development of proliferative retinopathy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0001-639X
pubmed:author
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
530-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Proliferative diabetic retinopathy: at risk patients identified by early detection of microalbuminuria.
pubmed:publicationType
Journal Article