Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1986-1-21
pubmed:abstractText
Ganglioside GM1 was labeled with 125I either directly or after conjugation to tyramine. Direct iodination of the sphingosine chain resulted in a compound which dehalogenated rapidly both in vitro and in vivo. The binding of the 125I[GM1-tyramine] conjugate to neuronal membranes in vitro was similar to that reported for 3H-GM1. The biodistribution of 125I activity after intravenous injection of 0.5 uM and 5 uM 125I[GM1-tyramine] in mice was also similar to that reported for 3H-GM1. This radioiodinated GM1 derivative might be useful for the study of ganglioside GM1 function in vivo.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0031-6989
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
897-912
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Radioiodinated ganglioside GM1: a potential tool for the investigation of ganglioside function in vivo.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't