Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1986-1-9
pubmed:abstractText
The interaction of 111Indium-labeled platelets, and other blood components with the luminal surface of polydimethylsiloxane (PDMS) and low-density polyethylene (LDPE) was determined using an ex vivo arteriovenous shunt in the baboon. Both PDMS and LDPE showed little platelet accumulation at either high (200 cc/min) flow rates. PDMS accumulated more platelets at low than at high flow. When the surfaces of PDMS and LDPE were examined under scanning electron microscopy after 2.5 h of flow in the shunt circuit, red and white blood cells were attached. Platelets appeared to be confined to patchy areas covered by a fibrinlike network. The low platelet reactivity of LDPE and PDMS suggests their potential use as coatings for conventional, more platelet reactive vascular graft materials.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0021-9304
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
577-87
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
The interaction of blood components with PDMS (polydimethylsiloxane) and LDPE (low-density polyethylene) in a baboon ex vivo arteriovenous shunt model.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't