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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1986-1-9
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pubmed:abstractText |
The interaction of 111Indium-labeled platelets, and other blood components with the luminal surface of polydimethylsiloxane (PDMS) and low-density polyethylene (LDPE) was determined using an ex vivo arteriovenous shunt in the baboon. Both PDMS and LDPE showed little platelet accumulation at either high (200 cc/min) flow rates. PDMS accumulated more platelets at low than at high flow. When the surfaces of PDMS and LDPE were examined under scanning electron microscopy after 2.5 h of flow in the shunt circuit, red and white blood cells were attached. Platelets appeared to be confined to patchy areas covered by a fibrinlike network. The low platelet reactivity of LDPE and PDMS suggests their potential use as coatings for conventional, more platelet reactive vascular graft materials.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0021-9304
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
577-87
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:4066730-Animals,
pubmed-meshheading:4066730-Arteriovenous Shunt, Surgical,
pubmed-meshheading:4066730-Biocompatible Materials,
pubmed-meshheading:4066730-Blood Physiological Phenomena,
pubmed-meshheading:4066730-Blood Platelets,
pubmed-meshheading:4066730-Blood Vessel Prosthesis,
pubmed-meshheading:4066730-Cell Adhesion,
pubmed-meshheading:4066730-Dimethylpolysiloxanes,
pubmed-meshheading:4066730-Male,
pubmed-meshheading:4066730-Microscopy, Electron, Scanning,
pubmed-meshheading:4066730-Papio,
pubmed-meshheading:4066730-Polyethylenes,
pubmed-meshheading:4066730-Regional Blood Flow
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pubmed:articleTitle |
The interaction of blood components with PDMS (polydimethylsiloxane) and LDPE (low-density polyethylene) in a baboon ex vivo arteriovenous shunt model.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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