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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
1986-1-23
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pubmed:databankReference |
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pubmed:abstractText |
We have determined the complete nucleotide sequence of a human DNA fragment of approximately 13 kbp, which was shown by Southern blot analysis to contain the entire v-fes/fps cellular homolog. The v-fes/fps homologous sequences were dispersed over 11 kbp in 18 interspersed segments which were flanked by splice junctions. Fusion of these segments created a DNA fragment in which coding regions similar to those observed in the viral oncogenes v-fes of the Gardner-Arnstein (GA) and Snyder-Theilen (ST) strains of feline sarcoma virus and v-fps found in Fujinami sarcoma virus could be identified. A potential initiation site in the first exon was found. About 200 nucleotides downstream of a translational stop codon in the v-fes/fps homologous region, a poly(A) addition signal was identified. The deduced amino acid sequence has a molecular weight of 93 390 dalton resembling NCP92, the recently described human c-fes/fps product. The topography of human c-fes/fps appeared to resemble that of chicken c-fps.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-225544,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-271968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-2982404,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-2983222,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-2986115,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-2987674,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-2993104,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-3879969,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-5444620,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-5774407,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6164154,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6166387,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6183005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6243819,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6245259,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6251261,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6251274,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6254060,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6256742,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6257397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6259536,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6261011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6262821,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6263483,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6264108,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6264151,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6277911,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6281890,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6283546,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6290870,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6291784,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6295880,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6298463,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6299580,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6301150,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6304726,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6328312,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6351725,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6538699,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-6582485,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-7031900,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-7063411,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-7094017,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-7099970,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4065096-7430166
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0261-4189
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2897-903
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:4065096-Amino Acid Sequence,
pubmed-meshheading:4065096-Animals,
pubmed-meshheading:4065096-Base Composition,
pubmed-meshheading:4065096-Base Sequence,
pubmed-meshheading:4065096-Chickens,
pubmed-meshheading:4065096-Cosmids,
pubmed-meshheading:4065096-Humans,
pubmed-meshheading:4065096-Nucleic Acid Hybridization,
pubmed-meshheading:4065096-Proto-Oncogenes,
pubmed-meshheading:4065096-Sequence Homology, Nucleic Acid
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pubmed:year |
1985
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pubmed:articleTitle |
The structure of the human c-fes/fps proto-oncogene.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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