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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1980-1-28
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pubmed:abstractText |
1 Slow-reacting substance of anaphylaxis (SRS-A) was produced by antigen challenge of passively sensitized human lung and actively sensitized guinea-pig lung. 2 A slow-reacting substance (SRS) was prepared from the peritoneal fluid of rats treated with calcium ionophore A23187. 3 These substances were extensively purified by charcoal adsorption, Sephadex G-15 gel filtration, ether extraction and reverse phase high pressure liquid chromatography. 4 The three substances are pharmacologically, chemically and chromatographically indistinguishable. 5 Our data suggest that the same SRS entities are released from a variety of tissues and that these acidic lipids may have a wider physiological significance than just anaphylaxis.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0007-1188
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
179-84
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:40646-Animals,
pubmed-meshheading:40646-Autacoids,
pubmed-meshheading:40646-Chemistry, Physical,
pubmed-meshheading:40646-Chromatography, Gel,
pubmed-meshheading:40646-Chromatography, High Pressure Liquid,
pubmed-meshheading:40646-Guinea Pigs,
pubmed-meshheading:40646-Humans,
pubmed-meshheading:40646-Lung,
pubmed-meshheading:40646-Physicochemical Phenomena,
pubmed-meshheading:40646-Rats,
pubmed-meshheading:40646-SRS-A,
pubmed-meshheading:40646-Species Specificity
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pubmed:year |
1979
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pubmed:articleTitle |
Comparative studies on immunologically and non-immunologically produced slow-reacting substances from man, guinea-pig and rat.
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pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro
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