|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
1986-1-15
|
|
pubmed:abstractText |
Complexes and covalent conjugates of protein antigens with polyelectrolytes of different molecular mass have been synthesised. The structure and composition of the resulting water-soluble complex particles were determined. Artificial antigen immunogenicity was shown to depend on the amount of protein molecules complexed with polyelectrolytes. Direct correlation between immunostimulating activity of the polymer-carrier, immunogenicity of complex antigens and size-dependent capacity of the polymer molecule to aggregate protein globules has been established.
|
|
pubmed:language |
rus
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0365-9615
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
100
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
597-600
|
|
pubmed:dateRevised |
2008-10-8
|
|
pubmed:meshHeading |
pubmed-meshheading:4063511-Acrylic Resins,
pubmed-meshheading:4063511-Animals,
pubmed-meshheading:4063511-Antibody Formation,
pubmed-meshheading:4063511-Antibody-Producing Cells,
pubmed-meshheading:4063511-Antigens,
pubmed-meshheading:4063511-Cell Count,
pubmed-meshheading:4063511-Immunization,
pubmed-meshheading:4063511-Mice,
pubmed-meshheading:4063511-Polyvinyls,
pubmed-meshheading:4063511-Serum Albumin, Bovine,
pubmed-meshheading:4063511-Spleen
|
|
pubmed:year |
1985
|
|
pubmed:articleTitle |
[Relation of the immunogenicity of artificial antigens to the number of polyelectrolyte-bound protein molecules].
|
|
pubmed:publicationType |
Journal Article,
English Abstract
|
