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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1986-1-16
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pubmed:abstractText |
Distinguishing cutaneous signs which are associated with hereditary cancer-prone syndromes are known as cancer-associated genodermatoses. Muir-Torre syndrome (M-T) is characterized by the occurrence of sebaceous hyperplasia, adenoma and carcinoma, basal cell carcinoma with sebaceous differentiation, and/or keratoacanthoma in association with visceral cancer (often multiple), and improved survival. Family studies of M-T have been either wholly lacking or too incomplete to elucidate hereditary aetiology. We describe the cutaneous phenotype of M-T in an extended kindred with a possible variant of the Cancer Family Syndrome. We emphasize the need for more thorough documentation of family histories and cancer association in this cancer-associated genodermatosis in order to clarify hereditary syndrome identification, and to improve cancer control through employment of cutaneous signs as a beacon for highly targeted forms of visceral cancer.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0007-0963
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
113
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
295-301
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:4063166-Adolescent,
pubmed-meshheading:4063166-Adult,
pubmed-meshheading:4063166-Aged,
pubmed-meshheading:4063166-Colonic Neoplasms,
pubmed-meshheading:4063166-Female,
pubmed-meshheading:4063166-Humans,
pubmed-meshheading:4063166-Hyperplasia,
pubmed-meshheading:4063166-Keratoacanthoma,
pubmed-meshheading:4063166-Male,
pubmed-meshheading:4063166-Middle Aged,
pubmed-meshheading:4063166-Neoplasms, Multiple Primary,
pubmed-meshheading:4063166-Pedigree,
pubmed-meshheading:4063166-Sebaceous Glands,
pubmed-meshheading:4063166-Skin Diseases,
pubmed-meshheading:4063166-Skin Neoplasms,
pubmed-meshheading:4063166-Syndrome
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pubmed:year |
1985
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pubmed:articleTitle |
Muir-Torre syndrome in several members of a family with a variant of the Cancer Family Syndrome.
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pubmed:publicationType |
Journal Article
|