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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1985-12-5
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pubmed:abstractText |
Enantiomers of nine K-region and one non-K-region epoxides of polycyclic aromatic hydrocarbons have been resolved by high-performance liquid chromatography with chiral stationary phases either ionically or covalently bonded to gamma-aminopropylsilanized silica. Resolution of enantiomers was confirmed by ultraviolet-visible absorption, circular dichroism, and mass spectral analyses. This method has been applied to the determination of optical purity and absolute configuration of the K-region epoxides formed in the metabolism of 1-methylbenz[a]anthracene, 7-methylbenz[a]anthracene, and 12-methylbenz[a]anthracene by rat liver microsomes.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0003-2697
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
148
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
328-38
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:4061813-Animals,
pubmed-meshheading:4061813-Chromatography, High Pressure Liquid,
pubmed-meshheading:4061813-Circular Dichroism,
pubmed-meshheading:4061813-Epoxy Compounds,
pubmed-meshheading:4061813-Ethers, Cyclic,
pubmed-meshheading:4061813-Male,
pubmed-meshheading:4061813-Microsomes, Liver,
pubmed-meshheading:4061813-Polycyclic Compounds,
pubmed-meshheading:4061813-Rats,
pubmed-meshheading:4061813-Rats, Inbred Strains,
pubmed-meshheading:4061813-Spectrophotometry, Ultraviolet,
pubmed-meshheading:4061813-Stereoisomerism
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pubmed:year |
1985
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pubmed:articleTitle |
Resolution of epoxide enantiomers of polycyclic aromatic hydrocarbons by chiral stationary-phase high-performance liquid chromatography.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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