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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1985-12-2
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pubmed:abstractText |
The effect of topical budesonide on the human mucociliary transport in the nose was investigated utilizing the saccharin-dye test in 10 healthy volunteers. Measurements were made before treatment, after a single dose and after one week continuous treatment with either placebo or active substance. The design of the study was double blind, randomized and cross-over. A single dose of placebo or budesonide did not alter the mucociliary transport as compared to pretreatment values. A trend towards decrease of mucociliary transport was noted after one week treatment with the active drug, a trend that reached statistical significance in the comparison between the 1 h value and the 1 week value.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0300-0729
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
23
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
181-5
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:4059802-Administration, Topical,
pubmed-meshheading:4059802-Adolescent,
pubmed-meshheading:4059802-Adult,
pubmed-meshheading:4059802-Biological Transport,
pubmed-meshheading:4059802-Budesonide,
pubmed-meshheading:4059802-Cilia,
pubmed-meshheading:4059802-Coloring Agents,
pubmed-meshheading:4059802-Female,
pubmed-meshheading:4059802-Humans,
pubmed-meshheading:4059802-Male,
pubmed-meshheading:4059802-Middle Aged,
pubmed-meshheading:4059802-Nasal Mucosa,
pubmed-meshheading:4059802-Nose,
pubmed-meshheading:4059802-Pregnenediones,
pubmed-meshheading:4059802-Saccharin,
pubmed-meshheading:4059802-Time Factors
|
pubmed:year |
1985
|
pubmed:articleTitle |
Mucociliary transport in the human nose. Effect of topical glucocorticoid treatment.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|