pubmed-article:4059031 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:4059031 | lifeskim:mentions | umls-concept:C0006675 | lld:lifeskim |
pubmed-article:4059031 | lifeskim:mentions | umls-concept:C0012984 | lld:lifeskim |
pubmed-article:4059031 | lifeskim:mentions | umls-concept:C0027061 | lld:lifeskim |
pubmed-article:4059031 | lifeskim:mentions | umls-concept:C0035253 | lld:lifeskim |
pubmed-article:4059031 | lifeskim:mentions | umls-concept:C0013790 | lld:lifeskim |
pubmed-article:4059031 | lifeskim:mentions | umls-concept:C1948023 | lld:lifeskim |
pubmed-article:4059031 | lifeskim:mentions | umls-concept:C0678640 | lld:lifeskim |
pubmed-article:4059031 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:4059031 | pubmed:dateCreated | 1985-12-3 | lld:pubmed |
pubmed-article:4059031 | pubmed:abstractText | 45Ca2+ exchange was studied in small pieces of canine left ventricular free wall. The loss of 45Ca2+ from 45Ca2+ equilibrated tissue into ice-cold (4 degrees C) "wash" medium could be best fitted with a model containing a minimum of 3 compartments. 45Ca2+ uptake into and 45Ca2+ efflux from the most slowly exchanging compartment (compartment 3) at 37 degrees C allowed it to be subdivided into two fractions; a rapidly exchanging fraction (t1/2 approximately 1.25 min) and a slowly exchanging fraction (t1/2 approximately 50 min). The total Ca2+ content of compartment 3 was enhanced by isoproterenol but little affected by caffeine. The slow t1/2 for exchange of the Ca2+ in compartment 3 at 4 degrees C and its increased Ca2+ content following isoproterenol treatment suggest that this compartment contains some Ca2+ of intracellular origin. In addition, the finding that the rapidly exchanging part of compartment 3 could be preserved by cooling the tissue to 4 degrees C shows that rapidly exchanging Ca2+ compartments can be studied in superfused cardiac preparations using this technique. Action potentials, elicited by electrical stimulation of the tissue, caused large changes in the Ca2+ content of compartment 3 (up to 170 muM/kg) indicating that this postulated intracellular compartment may play a significant role in the normal contraction-relaxation cycle. | lld:pubmed |
pubmed-article:4059031 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:4059031 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:4059031 | pubmed:language | eng | lld:pubmed |
pubmed-article:4059031 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:4059031 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:4059031 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:4059031 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:4059031 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:4059031 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:4059031 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:4059031 | pubmed:month | Sep | lld:pubmed |
pubmed-article:4059031 | pubmed:issn | 0031-6768 | lld:pubmed |
pubmed-article:4059031 | pubmed:author | pubmed-author:BassettA LAL | lld:pubmed |
pubmed-article:4059031 | pubmed:author | pubmed-author:GelbandHH | lld:pubmed |
pubmed-article:4059031 | pubmed:author | pubmed-author:LodgeN JNJ | lld:pubmed |
pubmed-article:4059031 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:4059031 | pubmed:volume | 405 | lld:pubmed |
pubmed-article:4059031 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:4059031 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:4059031 | pubmed:pagination | 37-45 | lld:pubmed |
pubmed-article:4059031 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:4059031 | pubmed:year | 1985 | lld:pubmed |
pubmed-article:4059031 | pubmed:articleTitle | Calcium exchange in the resting and electrically stimulated canine myocardium. | lld:pubmed |
pubmed-article:4059031 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:4059031 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:4059031 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |