Linked Life Data

4056096

Source:http://linkedlifedata.com/resource/pubmed/id/4056096

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1985-11-29
pubmed:abstractText
The microtubular content and caliber of sensory axons were studied in the L7 dorsal root, at the distal pole of the L7 spinal ganglion, and in the sural nerve of cats. Calibers of myelinated axons were symmetrical about the ganglion. In contrast, nonmedullated axons were strikingly different; 80% of the population at the root were smaller than 0.4 micron2, whilst just across the ganglion the same group was less than 20%. The microtubule densities of myelinated axons of the root were 11.8 and 6.1 microtubules/micron2 for 3- and 10 microns diameter axons, respectively. Across the ganglion the densities of myelinated axons of equal sizes were 24.2 and 14.4 microtubules/micron2, respectively. These values represent an approximate ratio of 1:2 between central and peripheral microtubule densities. Microtubule densities for nonmedullated axons also decreased with the increase in the cross-sectional area. The densities of root nonmedullated axons ranged between 90 and 10 microtubules/micron2; these were smaller, usually by a factor of three, than the densities of peripheral axons of a similar size (range: 367-44). Contrasting with the differences observed across the ganglion, the microtubular content and caliber of sensory axons seems to be quite uniform along their peripheral course. This is supported by the similar values found in the juxtaganglionic and sural nerves. It is estimated that an axon that contains 90 microtubules/micron2 has 26.7 mg of tubulin per ml of axoplasm in its assembled form, and 3.0 mg/ml if it contains 10 microtubules/micron2; these values are the practical limits of assembled tubulin in axoplasms.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0021-9967
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
236
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
258-64
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Microtubules and caliber of central and peripheral processes of sensory axons.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't