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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1985-12-10
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pubmed:abstractText |
High-performance liquid chromatographic (HPLC) analysis of human serum albumin (HSA) on a GS-520 column with 0.03 M sodium phosphate buffer-0.15 M sodium sulphate (pH 6.87) showed three peaks, the principal component corresponding to human mercaptalbumin (HMA) and the secondary and tertiary components to nonmercaptalbumin (HNA). Using HPLC analysis, the nonmercapt----mercapt conversion of HSA during haemodialysis and the mercapt----nonmercapt conversion after haemodialysis in chronic renal failure were re-confirmed, indicating that HMA is a covalent carrier protein for sulphur-containing amino acids. Fractions of HMA in various liver diseases were significantly lower than those of healthy male adults.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0021-9673
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
20
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pubmed:volume |
332
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
19-27
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:4055942-Adult,
pubmed-meshheading:4055942-Carrier Proteins,
pubmed-meshheading:4055942-Chromatography, High Pressure Liquid,
pubmed-meshheading:4055942-Cystine,
pubmed-meshheading:4055942-Humans,
pubmed-meshheading:4055942-Kidney Failure, Chronic,
pubmed-meshheading:4055942-Liver Diseases,
pubmed-meshheading:4055942-Male,
pubmed-meshheading:4055942-Renal Dialysis,
pubmed-meshheading:4055942-Serum Albumin,
pubmed-meshheading:4055942-Sulfhydryl Compounds
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pubmed:year |
1985
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pubmed:articleTitle |
High-performance liquid chromatographic studies on non-mercapt in equilibrium with mercapt conversion of human serum albumin. II.
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pubmed:publicationType |
Journal Article
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