Linked Life Data

4055940

Source:http://linkedlifedata.com/resource/pubmed/id/4055940

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1985-12-10
pubmed:abstractText
This paper proposes a retention model which predicts that the displacement of non-polar solutes from a reversed-phase chromatographic column is accompanied by the adsorption of a stoichiometric number (Z) of solvent molecules. The number of solvent molecules involved in this process is a function of both solute and solvent contact surface areas. Increasing solute contact surface area would increase Z whereas increasing solvent contact surface area would decrease the Z value for a specific solute. The experimental observations presented are consistent with this model. Further predictions of the model are that (1) plots of log k' versus the inverse log of solvent concentration will be non-linear at solvent concentrations where the surface of a reversed-phase support is not fully solvated, and (2) only a portion of the total non-polar surface area of a molecule actually contacts the surface of a reversed-phase support. Non-linearity in plots of log k' versus the inverse log of solvent concentration was in fact observed at solvent concentrations where solvation of the reversed-phase support is incomplete.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0021-9673
pubmed:author
pubmed:issnType
Print
pubmed:day
20
pubmed:volume
332
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
147-68
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Stoichiometric displacement of solvent by non-polar solutes in reversed-phase liquid chromatography.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.