Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1985-12-19
pubmed:abstractText
Serum amyloid A protein (SAA) and C-reactive protein (CRP) are acute-phase reactants synthesized by the liver. A close relationship was found between SAA and CRP concentrations in various rheumatic diseases (rs = 0.74 to 0.83). The serum concentration of these proteins reflected the activity of the rheumatic inflammation in a sensitive way. In secondary amyloidosis, persistently high SAA and CRP levels correlated closely with the progression of the renal amyloid manifestations. The findings show that measurements of SAA and CRP concentrations are valuable in assessing disease activity and the effect of therapy in rheumatic diseases, as well as in the assessment of the prognosis in secondary amyloidosis. Therapeutic measures that decrease SAA levels may reduce amyloid formation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0250-0868
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
405-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Clinical value of serum amyloid A and C-reactive protein measurements in secondary amyloidosis.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't