Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1985-11-5
pubmed:abstractText
Solitary desmoplastic trichoepitheliomas from a mother and two daughters were studied by conventional and electron microscopy. Differential diagnosis by conventional microscopy is briefly discussed. The lesions consisted of cords and nests of basaloid cells set in fibrotic stroma and confined to the dermis. In addition, each lesion contained horn cysts and focal areas of calcification. Horn cysts were occasionally identified in continuity with infundibulae of normal hair follicles. Semithin sections showed cords and nests of cells in continuity with the horn cysts. Ultrastructurally, a continuous basal lamina surrounded the cords of basaloid cells and connected to horn cysts. Individual cells contained tonofilaments and were attached to adjacent cells by desmosomes. Hemidesmosomes were present at peripheral cell membranes bounded by basal lamina. There was no glandular differentiation. Our observations by electron and conventional microscopy support a conclusion that desmoplastic trichoepitheliomas are derived from hair appendages.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0193-1091
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
277-82
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Solitary familial desmoplastic trichoepithelioma. A study by conventional and electron microscopy.
pubmed:publicationType
Journal Article, Case Reports