Linked Life Data

4050614

Source:http://linkedlifedata.com/resource/pubmed/id/4050614

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1985-11-18
pubmed:abstractText
Two populations of histaminocytes, with different sedimentation rates (SR), were separated by a computer developed isokinetic gradient using dispersed rat gastric mucosal cells. Histamine content, histidine decarboxylase (HDC) activity and incorporation of radiolabelled histidine metabolites were used to assess the migration of specific cells throughout the gradients. One histaminocyte population, with cells of lower SR, contained high HDC activity and undetectable levels of histamine, whereas the other population, with cells of higher SR, contained lower HDC activity and high concentration of histamine. Both types of histaminocytes incorporated 3H-histidine metabolites. Electron microscopy showed that the fractions containing histaminocytes with lower SR had 3.5 times more endocrine ECL cells than the original population of dispersed fundic cells and lacked A and D cells, whereas the fractions with histaminocytes of higher SR were associated with a 2.7 times higher concentration of A and D cells and with a 7.7 times higher ratio of a variety of partial cells with a distinct mitochondrial morphology. These results are consistent with prior novel information regarding the separation of two populations of rat histaminocytes using different sedimentation techniques.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0065-4299
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
323-34
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Two biochemically distinct populations of histaminocytes separated by isokinetic sedimentation of dispersed rat gastric cells.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.