Linked Life Data

4047092

Source:http://linkedlifedata.com/resource/pubmed/id/4047092

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1985-11-6
pubmed:abstractText
Using phosphorus nuclear magnetic resonance spectroscopy, we studied the muscle metabolism in four patients with paramyotonia congenita as reflected in the PC/Pi and PC/ATP ratios. At normal body temperature, all results were indistinguishable from controls. After cooling to 29 degrees C muscle temperature and a single 2-sec maximum contraction, the forearm muscles were stiff. At this stage, no decrease in the ATP content could be detected. In greater than 50% of the experiments with patients, an additional peak occurred transiently at the resonant frequency for monophosphates. After a working period at 29 degrees C muscle temperature, the paramyotonic muscles were paralyzed, but displayed spectra similar to those obtained at normal body temperature and full working capability. Intracellular pH was close to 7 in paramyotonic muscle under all conditions examined.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0148-639X
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
606-10
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
In vivo P-NMR spectroscopy: muscle energy exchange in paramyotonia patients.
pubmed:publicationType
Journal Article