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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1985-10-25
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pubmed:abstractText |
Heparinised cord blood from newborns and peripheral venous blood from three other age groups of individuals (1-75 years) have been cultured in vitro to obtain baseline frequencies of SCE and to see if the frequency of baseline SCE in vitro varies as a function of aging in vivo. The results demonstrate an age-dependent variation in the frequency of SCEs. Although the SCE frequency was lowest (5.10/cell) in 1-5-year-old infants, a significantly higher (P less than 0.001) frequency (8.97/cell) was observed in the cord blood of newborns. In old age, the level of SCE also increased. The plausible reason(s) for such observations is discussed.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0027-5107
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
144
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
85-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:4047075-Adolescent,
pubmed-meshheading:4047075-Adult,
pubmed-meshheading:4047075-Age Factors,
pubmed-meshheading:4047075-Aged,
pubmed-meshheading:4047075-Aging,
pubmed-meshheading:4047075-Bromodeoxyuridine,
pubmed-meshheading:4047075-Cells, Cultured,
pubmed-meshheading:4047075-Child,
pubmed-meshheading:4047075-Child, Preschool,
pubmed-meshheading:4047075-Female,
pubmed-meshheading:4047075-Humans,
pubmed-meshheading:4047075-Infant,
pubmed-meshheading:4047075-Infant, Newborn,
pubmed-meshheading:4047075-Lymphocytes,
pubmed-meshheading:4047075-Male,
pubmed-meshheading:4047075-Middle Aged,
pubmed-meshheading:4047075-Reference Values,
pubmed-meshheading:4047075-Sex Factors,
pubmed-meshheading:4047075-Sister Chromatid Exchange
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pubmed:year |
1985
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pubmed:articleTitle |
Baseline frequency of sister-chromatid exchanges (SCE) in newborn lymphocytes and its relationship to in vivo aging in humans.
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pubmed:publicationType |
Journal Article
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