Linked Life Data

404601

Source:http://linkedlifedata.com/resource/pubmed/id/404601

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1977-6-11
pubmed:abstractText
Collagen was extracted with acid from fresh calf skin, reconstituted and crosslinked with one of four aldehydes, and implanted into surgically created defects in rabbit mandibles. All grafts were histocompatible, with no signs of infection or rejection. There was partial degradation of simple aldehyde cross-linked collagen grafts, with new bone formation evident throughout as early as 4 weeks and complete by 3 to 4 months. The greater the degree of aldehyde-induced cross-linking, the longer the time of degradation, with dialdehyde-fixed specimens not starting to degrade for 6 months and highly cross-linked grafts intact and stable after 1 year. In grafted animals the mandible regained its original contour, while in control animals a defect remained after 1 year.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0030-4220
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
677-86
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Collagen xenografts for bone replacement: the effects of aldehyde-induced cross-linking on degradation rate.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.