Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1985-11-15
pubmed:abstractText
We used an enzyme-linked immunosorbent assay system to compare prevalence and levels of systemic and local antibody to Giardia lamblia in different populations. Serial blood and milk samples were collected simultaneously from lactating women in Texas and Mexico. IgG antibody to G. lamblia was present in 118 (77%) of 153 sera from 27 Mexican mothers but in only 51 (24%) of 214 sera obtained from 28 Texan mothers (P less than .001). Sera positive for IgG antibody to G. lamblia revealed antibody levels that were significantly higher in Mexico than in Texas (0.325 +/- 0.076 vs. 0.219 +/- 0.079 optical density units). Secretory IgA antibody to G. lamblia was found in 121 (79%) of 153 milk samples in the Mexican population, but in only 33 (15%) of 214 samples in the Texan population (P less than .001). The levels of secretory antibody to G. lamblia also were higher in the Mexican population. The study documents a widely different antibody response to G. lamblia in individuals living in different areas. As antibodies to G. lamblia can be acquired by infants transplacentally or through breast-feeding, this difference might be important in the relative protection against giardial infection.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0022-1899
pubmed:author
pubmed:issnType
Print
pubmed:volume
152
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1025-31
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Prevalence of serum and milk antibodies to Giardia lamblia in different populations of lactating women.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't