Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-11-8
pubmed:abstractText
It has been established in male Wistar rats that the uptake capacity of the reticuloendothelial system (RES) increased 5-fold 1, 3 and 7 days after prodigiozan administration (50 micrograms). This was linked with the increased hepatocyte resistance to CCl4 which reached a maximum 7 and 21 days after RES stimulation. As compared with non-stimulated animals, the resistance increase looked as a 2.7- and 3.5-fold shrinkage of the necrotic zones in the central parts of liver lobules 24 h after CCl4 poisoning and less increment of alanine aminotransferase activity in blood serum (3.5- and 3.3-fold decrease, respectively). The increased resistance continued being recordable throughout a month after prodigiozan treatment.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0014-8318
pubmed:author
pubmed:issnType
Print
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
96-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Increased hepatocyte resistance to CC14 following the stimulation of rats with a bacterial polysaccharide].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract