Linked Life Data

4040544

Source:http://linkedlifedata.com/resource/pubmed/id/4040544

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1985-8-29
pubmed:abstractText
Nine greyhound dogs were fed ethanol for 1 year to examine the effects of long-term ethanol feeding on circulating thyroid hormones. The dose of ethanol consumed per day was 2 gm/kg for the first month, 3 gm/kg for the second month, and 4 gm/kg for the rest of the study. Plasma triiodothyronine (T3), thyroxine (T4), and reverse triiodothyronine (rT3) were measured by radioimmunoassay. Plasma T3 and T4 concentrations increased significantly during the period of ethanol administration compared with control values (ANOVA, P less than 0.005). Levels of rT3 showed a trend to increase, although this was not significant. Resin T3 uptake decreased significantly (ANOVA, P less than 0.005) and the calculated free T4 index and free T3 index showed significant elevations (ANOVA, P less than 0.005) during ethanol administration. The results of this study indicate that long-term ethanol feeding to dogs induces an increase in circulating thyroid hormones.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0022-2143
pubmed:author
pubmed:issnType
Print
pubmed:volume
106
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
141-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
One year of ethanol feeding increases circulating thyroid hormones in the dog.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.