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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1985-9-12
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pubmed:abstractText |
Twenty-five patients with advanced malignant mesothelioma were treated in a phase II trial with high-dose cisplatin (DDP). All patients had measurable or evaluable disease. Seven patients had received prior chemotherapy. DDP (120 mg/m2) with mannitol and prehydration was given every 4 weeks for two doses and then every 6 weeks. Of 24 patients evaluable for response, three had partial responses (3, 3+, and 9 months; response rate, 13%; 95% confidence limits, 4%-31%) and one had minor response. All responses occurred in previously untreated patients. High-dose DDP has modest activity in malignant mesothelioma.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
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pubmed:issn |
0361-5960
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
711-2
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:4040424-Aged,
pubmed-meshheading:4040424-Cisplatin,
pubmed-meshheading:4040424-Drug Evaluation,
pubmed-meshheading:4040424-Female,
pubmed-meshheading:4040424-Humans,
pubmed-meshheading:4040424-Kidney Diseases,
pubmed-meshheading:4040424-Male,
pubmed-meshheading:4040424-Mesothelioma,
pubmed-meshheading:4040424-Middle Aged,
pubmed-meshheading:4040424-Peritoneal Neoplasms,
pubmed-meshheading:4040424-Pleural Neoplasms
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pubmed:year |
1985
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pubmed:articleTitle |
Phase II trial of high-dose cisplatin in patients with malignant mesothelioma.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|