Linked Life Data

4040192

Source:http://linkedlifedata.com/resource/pubmed/id/4040192

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1985-8-5
pubmed:abstractText
A 25 micrograms dose of testosterone propionate injected at 4 days of age induced 90% anovulation at 100 days of age. The systemic administration of orciprenaline (8 or 16 micrograms) or yohimbine (100 micrograms) did not prevent androgenization. Twenty-five or fifty micrograms of orciprenaline injected intraventricularly reduced only partially (to 54 and 67% respectively) the effectiveness of androgenization. We concluded that beta-adrenergic receptor stimulation had a very limited ability to prevent androgenization, since the beta-stimulation obtained directly with orciprenaline prevented androgenization to a very limited extent, while the possible indirect stimulation through an increase in norepinephrine endogenous release by alpha-2 receptor blocker yohimbine was ineffective.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-4731
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
677-9
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Can neonatal beta-adrenergic stimulation prevent the effects of androgenization in female rats?
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't