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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1985-7-2
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pubmed:abstractText |
We have used electron microscopy and established methods of three-dimensional reconstruction to obtain structural information on the 30 nm chromatin fibers from sea cucumber sperm and chicken erythrocytes. The fibers show a longitudinal periodicity of 10-11 nm. We have interpreted this periodicity as due to a grouping of nucleosomes into disks, each disk containing about 5-6 nucleosomes. These disks are closely stacked to form the chromatin fiber. We have built a detailed model for four fibers and we have determined the approximate coordinates of all the nucleosomes in them. The average distance found between neighboring nucleosomes has a value close to 11 nm. They may be connected either as a regularly distorted helix or as a layered zigzag. The second model appears more appropriate, since in the constrictions of the fibers the nucleosomes can only be connected as a zigzag.
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pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0009-5915
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
91
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
377-90
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:4039646-Animals,
pubmed-meshheading:4039646-Chickens,
pubmed-meshheading:4039646-Chromatin,
pubmed-meshheading:4039646-Erythrocytes,
pubmed-meshheading:4039646-Male,
pubmed-meshheading:4039646-Microscopy, Electron,
pubmed-meshheading:4039646-Nucleosomes,
pubmed-meshheading:4039646-Sea Cucumbers,
pubmed-meshheading:4039646-Spermatozoa
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pubmed:year |
1985
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pubmed:articleTitle |
The layered organization of nucleosomes in 30 nm chromatin fibers.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|