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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1985-6-3
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pubmed:abstractText |
A total of 17 strains of Stachybotrys atra isolated in Hungary and Czechoslovakia were cultured on Sabouraud agar, and the toxins produced by them were chemically analyzed by gas-liquid chromatography, high-pressure liquid chromatography, and mass spectroscopy. Furthermore, brine shrimp (Artemia salina) bioassay was used for the determination of toxicity of the compounds examined. Macrocyclic trichothecenes (satratoxins H and G, roridin E, and verrucarin J as well as two other unidentified macrocyclic trichothecenes) were found in all of the cultures tested. The identities of satratoxins H and G, roridin E, and verrucarin J were qualitatively determined by high-pressure liquid chromatography and gas-liquid chromatography. The ratio of satratoxins H and G and roridin E was found to be similar in each of the strains tested, but the amount of verrucarin J found was different in each of them. One of the unidentified macrocyclic trichothecenes was equivalent to the compound isolated by Harrach et al. (Harrach et al., Appl. Environ. Microbiol. 41:1428-1433, 1981). The other one proved to be a newly isolated macrocyclic trichothecene toxin. Stachybotryotoxicosis, one of the oldest mycotoxicoses known, and a serious problem in Middle Europe (Gy. Danko, Magy. Allatorv. Lapja 31:226-232, 1976), is believed to be caused by macrocyclic trichothecene toxins produced by Stachybotrys atra (R. M. Eppley, in Rodricks et al., ed., Mycotoxins in Human and Animal Health, p. 285-293, 1977). Forty years ago, the death of animals in the Soviet Union was associated with this fungus (C. U. Ruhliada, in Proceedings of the All-Union Sci. and Tech. Conf., p. 47-51, 1980).(ABSTRACT TRUNCATED AT 250 WORDS)
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4039551-4737542,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4039551-4833398,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4039551-566066,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4039551-566068,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4039551-575906,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4039551-6683481,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4039551-6889838,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4039551-7191050,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4039551-7195684
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Sesquiterpenes,
http://linkedlifedata.com/resource/pubmed/chemical/Trichothecenes,
http://linkedlifedata.com/resource/pubmed/chemical/roridin E,
http://linkedlifedata.com/resource/pubmed/chemical/satratoxin G,
http://linkedlifedata.com/resource/pubmed/chemical/satratoxin H,
http://linkedlifedata.com/resource/pubmed/chemical/verrucarin J
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0099-2240
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
678-81
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading | |
pubmed:year |
1985
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pubmed:articleTitle |
Macrocyclic trichothecene toxins produced by Stachybotrys atra strains isolated in Middle Europe.
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pubmed:publicationType |
Journal Article
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