Linked Life Data

4039516

Source:http://linkedlifedata.com/resource/pubmed/id/4039516

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1985-6-13
pubmed:abstractText
The comparison of 32 immature infants with mental retardation of various degree (based on the results of clinical, immunological and biochemical examinations) with full-term infants with analogous pathology showed in the former group a high incidence (82.8%) of cerebral antibodies to antigens of the homo- and heterological brain in the complement consumption test. Therapeutic measures helped to reduce neuroimmune changes while the presence of antibodies to the homologous brain remained stable. Using data on the excretion of vanillyl amygdalic and homovanillic acids, the authors established alterations in catecholamine catabolism as well as in the activity of serum amine oxidase, which depended on the degree of mental retardation. Changes in individual components of catecholamine metabolism were found to correlate with neuroimmune shifts. The data obtained point to the presence of changes in biogenic amine metabolism and in immunological processes in mentally retarded children, which are very likely to be caused by immaturity at birth.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0044-4588
pubmed:author
pubmed:issnType
Print
pubmed:volume
85
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
388-94
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
[Clinico-pathogenetic correlations in intellectual deficiency in premature infants].
pubmed:publicationType
Journal Article, English Abstract