Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1985-6-6
|
pubmed:abstractText |
Thirty-seven patients with advanced malignancies, who received cis-platinum-based combination chemotherapy, were evaluated for the antiemetic efficacy of high-dose metoclopramide. Most of the patients suffered from ovarian carcinoma. The dose of metoclopramide was 7.5 or 10 mg/kg per course. A total of 69 courses were given to 37 patients and in 22% of the courses, nausea and vomiting were eliminated altogether. In an additional 48% of the courses, a partial protection from chemotherapy-induced emesis was evident. No serious side effects were observed. The administration of high-dose metoclopramide is recommended for prevention of cis-platinum chemotherapy-induced emesis.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0090-8258
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
21
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
18-22
|
pubmed:dateRevised |
2006-4-24
|
pubmed:meshHeading |
pubmed-meshheading:4039286-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:4039286-Cisplatin,
pubmed-meshheading:4039286-Diarrhea,
pubmed-meshheading:4039286-Female,
pubmed-meshheading:4039286-Humans,
pubmed-meshheading:4039286-Male,
pubmed-meshheading:4039286-Metoclopramide,
pubmed-meshheading:4039286-Middle Aged,
pubmed-meshheading:4039286-Ovarian Neoplasms,
pubmed-meshheading:4039286-Sleep Stages,
pubmed-meshheading:4039286-Tremor,
pubmed-meshheading:4039286-Trismus,
pubmed-meshheading:4039286-Vomiting
|
pubmed:year |
1985
|
pubmed:articleTitle |
High-dose metoclopramide as an antiemetic in patients receiving cis-platinum-based combination chemotherapy.
|
pubmed:publicationType |
Journal Article
|