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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1985-10-8
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pubmed:abstractText |
To study the transient diastolic murmur associated with renal failure, we used Doppler echocardiography to characterize flow across the semilunar valves in 10 patients on chronic hemodialysis with a diastolic murmur (group A), 26 patients on chronic hemodialysis without murmurs (group B), and 15 healthy persons (group C). Nine patients in group A had pulmonic valve insufficiency that encompassed 77 +/- 21% (SD) of diastole with peak regurgitant flow velocities of 1.7 +/- 0.3 m/s. Doppler-calculated mean pulmonary artery pressure in 8 of them was 43 +/- 7 mm Hg before dialysis and 20 +/- 12 mm Hg afterward (p less than 0.001). Dialysis reduced the duration of pulmonic insufficiency to 10 +/- 16% of diastole and lowered peak regurgitant flow velocities to 0.2 +/- 0.2 m/s (p less than 0.001 for each). Three patients in group B had aortic valve insufficiency and 3 had pulmonic valve insufficiency like that in group A. Three persons in group C had mild pulmonic valve insufficiency. Thus, transient diastolic murmurs associated with pulmonic valve insufficiency are not uncommon in patients with renal failure; they are related to fluid overload, are diminished by extracellular fluid removal, and reflect correctable pulmonary hypertension.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0003-4819
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
497-502
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:4037556-Adult,
pubmed-meshheading:4037556-Blood Flow Velocity,
pubmed-meshheading:4037556-Blood Pressure,
pubmed-meshheading:4037556-Diastole,
pubmed-meshheading:4037556-Echocardiography,
pubmed-meshheading:4037556-Heart Auscultation,
pubmed-meshheading:4037556-Heart Murmurs,
pubmed-meshheading:4037556-Humans,
pubmed-meshheading:4037556-Kidney Failure, Chronic,
pubmed-meshheading:4037556-Middle Aged,
pubmed-meshheading:4037556-Pulmonary Artery,
pubmed-meshheading:4037556-Pulmonary Valve Insufficiency,
pubmed-meshheading:4037556-Renal Dialysis,
pubmed-meshheading:4037556-Ultrafiltration
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pubmed:year |
1985
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pubmed:articleTitle |
Pulmonic valve insufficiency: a common cause of transient diastolic murmurs in renal failure.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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