Linked Life Data

4037530

Source:http://linkedlifedata.com/resource/pubmed/id/4037530

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1985-10-4
pubmed:abstractText
We prospectively evaluated lower respiratory secretions obtained by bronchoalveolar lavage and stained with Oil-Red-O in patients with a variety of parenchymal diseases and in normal subjects. Our subjects included aspirators (n = 9), nonaspirators (n = 40), and normal subjects (n = 9). By grading the amount of intracellular Oil-Red-O per 100 alveolar macrophages, we computed a semiquantitative, lipid-laden alveolar macrophage index. The mean index for aspirators of 207 +/- 80 was significantly greater than the mean indexes of nonaspirators (121 +/- 97, p less than 0.02) and normal subjects (0.6 +/- 1.7, p less than 0.001). An index of greater than or equal to 100 had a sensitivity and negative predictive value of 100% each, a false negative rate of 0%, and a specificity of 57%. We conclude that (1) the mere presence of lipid-laden alveolar macrophages in lower respiratory secretions is a nonspecific marker of parenchymal lung disease; (2) the computation of a lipid-laden alveolar macrophage index may be helpful in excluding aspiration as a cause of parenchymal lung disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0003-0805
pubmed:author
pubmed:issnType
Print
pubmed:volume
132
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
576-81
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
The lipid-laden alveolar macrophage as a marker of aspiration in parenchymal lung disease.
pubmed:publicationType
Journal Article, Comparative Study