Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1985-10-22
pubmed:abstractText
An ultrastructural comparison was made between the motor cortex synapses of the brain of 4 adult Brown Swiss cattle with weaver syndrome and 2 healthy cattle (a Holstein steer and a Guernsey cow). Compared with the healthy cattle, the paramembranous densities at synaptic junctions of cattle with weaver syndrome had a decreased mean height of the presynaptic dense projections (P less than 0.001), had significantly smaller peak-to-peak distances (P less than 0.001), and had a significantly decreased mean thickness of the postsynaptic density (P less than 0.0001). These synaptic changes in cattle with weaver syndrome may be associated with clinical manifestations of the syndrome, such as impairment of transmitter release, instability of postsynaptic receptor sites, lesion-induced synaptic turnover from injury elsewhere in the CNS, or loss of a specific cell population of the motor cortex.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0002-9645
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1733-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Ultrastructural alterations of motor cortex synaptic junctions in Brown Swiss cattle with weaver syndrome.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.