Linked Life Data

403742

Source:http://linkedlifedata.com/resource/pubmed/id/403742

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1977-5-20
pubmed:abstractText
In 15 patients with pernicious anemia, the fractional retention of 58Co-cyanocobalamin (FRB12) without administration of intrinsic factor (IF) averaged 4.9% (range 0-12.7). With administration of IF, FRB12 averaged 32.7% (range 26.6--42.3) in the patients and 65.6% (range 38.8--84.6) in 16 control subjects. The gut transit time for vitamin B12 was evaluated from the excretion of radiopaque pellets given concomitantly with the 58Co-vitamin B12. The retention of the pellets was positively correlated to that of the non-absorbed 58Co-B12. Control of the gut transit time is recommended at each examination of FRB12 in order to avoid falsely high values due to the retention of non-absorbed 58Co-B12. We found a good reproducibility of FRB12 when determined in fasting subjects, and it is therefore unnecessary to give the patients a B12-free meal prior to the examination. As the FRB12 in all probability is only a little lower than the fractional absorption, the present method is applicalble for the determination of B12 absorption.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-6101
pubmed:author
pubmed:issnType
Print
pubmed:volume
201
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
167-71
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Determination of 58Co-vitamin B12 absorption in pernicious anemia by use of whole-body counting: Reproducibility and control of gut transit time.
pubmed:publicationType
Journal Article