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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1985-10-9
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pubmed:abstractText |
This study assesses the clinical feasibility and usefulness of dipyridamole infusion for the detection of coronary artery disease (CAD) by using 2-dimensional echocardiography (2-D echo) and 12-lead electrocardiographic monitoring. Dipyridamole infusion (0.14 mg/kg/min for 4 minutes) was performed in 66 consecutive patients with effort chest pain and in 9 control subjects. Among the 28 patients with positive dipyridamole-echocardiography test responses, 18 had diagnostic electrocardiographic changes (ST-segment depression on anterolateral leads), but these changes were unrelated to the site of asynergy. The dipyridamole-echocardiography test had an overall sensitivity of 56% and specificity of 100% for the presence of CAD. Exercise stress testing (EST) had an overall sensitivity of 62% and a specificity of 80%. Thus, the dipyridamole-echocardiography test, which is feasible in essentially all patients with good basal echocardiograms, has a lower overall sensitivity in detecting CAD than EST but a higher specificity, detects the site of apparent ischemia as identified by regional asynergy more precisely than EST, and can unmask electrocardiographically silent effort ischemia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0002-9149
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
1
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pubmed:volume |
56
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
452-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:4036826-Adult,
pubmed-meshheading:4036826-Aged,
pubmed-meshheading:4036826-Angiography,
pubmed-meshheading:4036826-Coronary Disease,
pubmed-meshheading:4036826-Dipyridamole,
pubmed-meshheading:4036826-Echocardiography,
pubmed-meshheading:4036826-Electrocardiography,
pubmed-meshheading:4036826-Female,
pubmed-meshheading:4036826-Humans,
pubmed-meshheading:4036826-Infusions, Parenteral,
pubmed-meshheading:4036826-Male,
pubmed-meshheading:4036826-Middle Aged
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pubmed:year |
1985
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pubmed:articleTitle |
Dipyridamole-echocardiography test in effort angina pectoris.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|