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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1985-10-7
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pubmed:abstractText |
The performance of the dexamethasone suppression test (DST) in the diagnostic confirmation of endogenous depression was compared according to two times of blood collection--1600 hr on day 2 (usual sample) and 0800 hr on day 3 (34 hr after dexamethasone intake)--in 14 endogenous depressives and in a control group of 17 psychiatric inpatients with other diagnoses. For the day 2 (1600 hr) sample, a 5 micrograms/dl cortisol concentration represented the best cut-off score, with sensitivity of 57% specificity of 88%, and diagnostic confidence of 80%. For the day 3 (0800 hr) sample, the best cut-off score was 20 micrograms/dl, with the same sensitivity (57%) but there was a decrease of both specificity (to 76%) and diagnostic confidence (to 67%). The mean cortisol levels were much higher on day 3 than on day 2, suggesting that the inhibitory activity of dexamethasone was no longer present.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0306-4530
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
215-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:4034851-Adult,
pubmed-meshheading:4034851-Aged,
pubmed-meshheading:4034851-Circadian Rhythm,
pubmed-meshheading:4034851-Depressive Disorder,
pubmed-meshheading:4034851-Dexamethasone,
pubmed-meshheading:4034851-Female,
pubmed-meshheading:4034851-Humans,
pubmed-meshheading:4034851-Hydrocortisone,
pubmed-meshheading:4034851-Male,
pubmed-meshheading:4034851-Middle Aged
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pubmed:year |
1985
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pubmed:articleTitle |
Diagnostic performance of the thirty-four hour dexamethasone suppression test.
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pubmed:publicationType |
Journal Article
|