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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
718
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pubmed:dateCreated |
1985-10-17
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pubmed:abstractText |
Twenty-eight patients with wide spectrum organ involvement of progressive systemic sclerosis but without signs or symptoms suggestive of cardiac involvement were studied by non-invasive cardiac techniques. The 12-lead electrocardiogram showed abnormalities in 6 patients: one had abnormal T waves and 5 had complete or incomplete right bundle branch block. Twenty-four hour ambulatory electrocardiography demonstrated higher average heart rates than in similar aged controls (82 +/- 9 vs 74 +/- 9 beats/min, P less than 0.05). In one patient a short run of ventricular tachycardia was recorded. No other significant arrhythmia was documented. Echocardiographic measurements were within normal ranges but small pericardial effusions were observed in two patients (7%). Resting first pass radionuclide angiography, utilizing 12 mCi of technetium 99m were performed in 23 patients. Seven patients (30%) had abnormal wall motion (diffuse hypokinesia), with a significant decrease in ejection fraction in comparison to those with normal wall motion (44 +/- 6% vs 60 +/- 6% P less than 0.01). Those with abnormal wall motion had suffered the disease longer than those with normal wall motion (13 +/- 4 vs 9.5 +/- 7 y). In conclusion, the heart is involved in half of the patients in this series; non-invasive cardiac assessment is useful in disclosing the early cardiac involvement and may influence long-term management.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-1248080,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-13594829,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-13731087,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-14297523,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-154294,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-4104697,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-426958,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-4279550,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-4425013,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-5780367,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-5929661,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-5942938,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-6275870,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-6339245,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-636997,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-6690931,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-685851,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-7030042,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-709763,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-7105507,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-7238556,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-7246582,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-7421930,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-7437174,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-7437193,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-74472,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-7447221,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-7469209,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4034457-961700
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0032-5473
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
679-84
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:4034457-Adult,
pubmed-meshheading:4034457-Aged,
pubmed-meshheading:4034457-Arrhythmias, Cardiac,
pubmed-meshheading:4034457-Cardiomyopathies,
pubmed-meshheading:4034457-Echocardiography,
pubmed-meshheading:4034457-Electrocardiography,
pubmed-meshheading:4034457-Female,
pubmed-meshheading:4034457-Heart,
pubmed-meshheading:4034457-Heart Rate,
pubmed-meshheading:4034457-Humans,
pubmed-meshheading:4034457-Male,
pubmed-meshheading:4034457-Middle Aged,
pubmed-meshheading:4034457-Scleroderma, Systemic
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pubmed:year |
1985
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pubmed:articleTitle |
Non-invasive assessment of early cardiac involvement in systemic sclerosis.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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