Linked Life Data

4033899

Source:http://linkedlifedata.com/resource/pubmed/id/4033899

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1985-10-8
pubmed:abstractText
A new experimental paradigm for studying cognitive functions by means of endogenous event-related brain potentials is presented. The paradigm has the following characteristics: (1) subcomponents of 'P300' (P3a, P3b, positive slow wave) and subcomponents of 'CNV' (early and late wave) are separated in time; (2) probability effects known to work on P300 subcomponents are completely under experimental control; and (3) psychologically defined antecedent conditions which affect particular endogenous components can be manipulated precisely and independently of each other. The usefulness of the paradigm for monitoring pharmacopsychological effects on cognitive functions is exemplified by means of flupentixol (Fluanxol 0.5). Reliable drug effects were observed with a dosage of 2 mg/day after 4 days of treatment. The results can be taken as evidence that flupentixol has an impairing effect on human information processing resources; in particular functions related to motor preparation, perceptual analysis, and memory retrieval are affected.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0302-282X
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
81-92
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Delineation of pharmacopsychological effects by means of endogenous event-related brain potentials: an exemplification with flupentixol.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't