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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1985-10-7
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pubmed:abstractText |
To study the usefulness of IgM hepatitis B core antibody (anti-HBc IgM) for detecting hepatitis B virus infections in infants of hepatitis B surface antigen (HBsAg) carrier mothers, serial serum samples from 86 infants of carrier mothers were tested for anti-HBc IgM with a highly specific enzyme immunoassay. Asymptomatic hepatitis B infection occurred frequently in infants under 12 mo of age. Anti-HBc IgM never became positive in 25 infants infected under 9 mo old. It was positive in only 1 of 6 infected at 9 mo and 4 of 13 infected at 12 mo of age. The IgM antibody lasted for less than 6 mo. Although the infection was delayed in 28 infants receiving hepatitis B immune globulin, the poor anti-HBc IgM response did not seem to be due to the immune prophylaxis. Our study clearly indicates the limitation of anti-HBc IgM for detecting acute hepatitis B infection in infants born to HBsAg carrier mothers.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Hepatitis B Core Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/Hepatitis B Surface Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/Hepatitis B e Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin M
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0146-6615
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
309-14
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:4031828-Adult,
pubmed-meshheading:4031828-Age Factors,
pubmed-meshheading:4031828-Carrier State,
pubmed-meshheading:4031828-Female,
pubmed-meshheading:4031828-Hepatitis B,
pubmed-meshheading:4031828-Hepatitis B Core Antigens,
pubmed-meshheading:4031828-Hepatitis B Surface Antigens,
pubmed-meshheading:4031828-Hepatitis B e Antigens,
pubmed-meshheading:4031828-Humans,
pubmed-meshheading:4031828-Immunization, Passive,
pubmed-meshheading:4031828-Immunoglobulin M,
pubmed-meshheading:4031828-Infant,
pubmed-meshheading:4031828-Taiwan
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pubmed:year |
1985
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pubmed:articleTitle |
Inadequacy of immunoglobulin M hepatitis B core antibody in detecting acute hepatitis B virus infection in infants of HBsAg carrier mothers.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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