Linked Life Data

4029396

Source:http://linkedlifedata.com/resource/pubmed/id/4029396

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1985-10-21
pubmed:abstractText
The site specificity of the removal of iron from diferric human transferrin, at pH 7.4, by two alpha-ketohydroxypyridine chelators, 1,2-dimethyl-3-hydroxypyrid-4-one (L1) and mimosine, has been investigated using urea-polyacrylamide gel electrophoresis. Chelator L1 removes iron preferentially from the C-terminal site whereas mimosine shows a small preference for iron in the N-terminal site. The removal of iron has also been followed spectrophotometrically and by monitoring the loss of 59Fe from [59Fe]transferrin. Both chelators are able to remove iron completely from diferric transferrin without additional mediators or reducing agents.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0014-5793
pubmed:author
pubmed:issnType
Print
pubmed:day
9
pubmed:volume
189
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
141-4
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Site specificity of iron removal from transferrin by alpha-ketohydroxypyridine chelators.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't