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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1985-10-15
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pubmed:abstractText |
Extracellular Mg2+ is known to inhibit the passive Na+ and K+ fluxes in the human erythrocyte. In this study the effect of extracellular Mg2+ on Li+ efflux was measured in erythrocytes from 29 normotensive and essential hypertensive subjects. Magnesium produced a variable inhibition of between 0 and 47% in Li+ efflux in different subjects and this effect was unrelated to initial cell Li+, blood pressure or to an action on the co- or counter-transport pathways for this cation. A positive correlation was observed between the magnitude of the passive Li+ efflux and its inhibition (0 to 47%) by Mg2+ ions. Thus Mg2+ has an inhibitory effect on passive Li+ permeability which is unrelated to essential hypertension.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0305-1870
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
311-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:4028517-Adult,
pubmed-meshheading:4028517-Cell Membrane Permeability,
pubmed-meshheading:4028517-Erythrocytes,
pubmed-meshheading:4028517-Humans,
pubmed-meshheading:4028517-Hypertension,
pubmed-meshheading:4028517-Lithium,
pubmed-meshheading:4028517-Magnesium,
pubmed-meshheading:4028517-Male,
pubmed-meshheading:4028517-Middle Aged,
pubmed-meshheading:4028517-Potassium,
pubmed-meshheading:4028517-Sodium
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pubmed:articleTitle |
Effect of magnesium on passive fluxes of lithium in the human erythrocyte.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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