Linked Life Data

4027623

Source:http://linkedlifedata.com/resource/pubmed/id/4027623

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1985-10-23
pubmed:abstractText
The autoradiographic technique was used to examine the projection from the digit and wrist area of the precentral gyrus to the putamen in two macaque monkeys. Motor responses elicited by intracortical microstimulation were mapped to guide selection of the site of injection of isotope. Additionally, an electrophysiological study of the activity of putamen neurons during voluntary movements of the distal arm in an awake monkey was performed prior to the anatomical study in one of the animals. Two major findings resulted from this study. Firstly, the area of representation of the digits and wrist in area 4 gives rise to a substantial projection to the putamen. The distribution of terminals consisted of a simple pattern of clusters at anterior levels of the putamen. At caudal levels in the putamen, the clusters merged into a single diagonal band of label. This basic pattern was found to be virtually identical in the two monkeys. Secondly, the location of neurons in the putamen which were activated during voluntary movements of the distal arm was closely associated with the terminal distribution of fibers from the digit and wrist zone of area 4. These data provide strong evidence to support the idea that the putamen is concerned with motor function of distal muscles of the arm, and that the topographic characteristics of the corticoputamen projection are closely related to the physiological properties of individual neurons in the putamen.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
339
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
245-55
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Projection of the digit and wrist area of precentral gyrus to the putamen: relation between topography and physiological properties of neurons in the putamen.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.