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pubmed:abstractText |
Isotopic data suggested a possible correlation between the activation of liver glycogen synthesis and some unstable intermediate. Carbamyl phosphate was one candidate considered. L-Norvaline, an inhibitor of ornithine transcarbamylase, is known to increase intracellular carbamyl phosphate levels. L-Norvaline augmented the increase in glycogen synthesis caused by L-glutamine and L-alanine, and also induced considerable glycogen synthesis with ammonia as the nitrogen source.
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