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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5-6
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pubmed:dateCreated |
1985-9-4
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pubmed:abstractText |
Chinchillas were maintained on a 1% cholesterol diet for 6 months. Auditory Brainstem Response (ABR) measurements were obtained before and at 1, 3, 5, and 6 months after initiation of diet. Compound Action Potential (AP) measurements were obtained at sacrifice at 6 months. A significant reduction in ABR was seen at 5 months-on-diet. At 5 months, the animals were exposed to a 2 octave bandpass noise centered at 1 kHz at 105 dB for 220 min. One month following noise exposure, the cholesterol-fed animals exhibited a greater ABR latency shift at low intensities, and an elevated AP threshold at higher frequencies, vis-à-vis a control group.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0001-6489
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
99
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
516-24
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:4024899-Animals,
pubmed-meshheading:4024899-Chinchilla,
pubmed-meshheading:4024899-Cochlea,
pubmed-meshheading:4024899-Diet, Atherogenic,
pubmed-meshheading:4024899-Environmental Exposure,
pubmed-meshheading:4024899-Evoked Potentials, Auditory,
pubmed-meshheading:4024899-Hyperlipidemias,
pubmed-meshheading:4024899-Lipids,
pubmed-meshheading:4024899-Noise,
pubmed-meshheading:4024899-Reaction Time
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pubmed:articleTitle |
Hyperlipidemia and noise in the chinchilla.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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