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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3 Suppl
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pubmed:dateCreated |
1985-9-19
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pubmed:abstractText |
It has been proposed that the blood group antibody, anti-P, produced by p or Pk individuals may cause abortion early in pregnancy. The authors have studied and successfully treated a Pk woman with anti-P who had 13 consecutive first-trimester miscarriages. Anti-P was implicated as the cause of repeated pregnancy loss after extensive clinical, endocrinologic, immunologic, and chromosomal evaluations. To remove P blood group antibodies, plasmapheresis was begun at five weeks' gestation during the 14th pregnancy with one plasma volume exchange two to three times per week. This therapy resulted in a reduction in the titer of anti-P, and the patient was delivered of a viable female infant after 33 weeks' gestation. The management and outcome indicate that habitual abortion presumably due to anti-P can be successfully treated with plasmapheresis. This case provides additional evidence that anti-P is responsible for abortions in p or Pk women, and that these abortions are immunologically mediated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0029-7844
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
57S-60S
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pubmed:dateRevised |
2009-10-26
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pubmed:meshHeading |
pubmed-meshheading:4022518-Abortion, Habitual,
pubmed-meshheading:4022518-Adult,
pubmed-meshheading:4022518-Antibodies,
pubmed-meshheading:4022518-Blood Group Antigens,
pubmed-meshheading:4022518-Female,
pubmed-meshheading:4022518-Humans,
pubmed-meshheading:4022518-P Blood-Group System,
pubmed-meshheading:4022518-Phenotype,
pubmed-meshheading:4022518-Plasma Exchange,
pubmed-meshheading:4022518-Plasmapheresis,
pubmed-meshheading:4022518-Pregnancy
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pubmed:year |
1985
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pubmed:articleTitle |
Plasmapheresis for the treatment of repeated early pregnancy wastage associated with anti-P.
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pubmed:publicationType |
Journal Article,
Case Reports
|